The molecular basis of muscular dystrophy in the mdx mouse: a point mutation
Journal Article
Sicinski, P., Geng, Y., Ryder-Cook, A., Barnard, E., Darlison, M., & Barnard, P. (1989)
The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science, 244(4912), 1578-1580. https://doi.org/10.1126/science.2662404
The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne muscular dystrophy. In both mouse and man the mutations lie within the dystrophin gene, but t...
Localization of GABAA receptor α-subunit mRNAs in relation to receptor subtypes
Journal Article
Wisden, W., Morris, B. J., Darlison, M. G., Hunt, S. P., & Barnard, E. A. (1989)
Localization of GABAA receptor α-subunit mRNAs in relation to receptor subtypes. Molecular Brain Research, 5(4), 305-310. https://doi.org/10.1016/0169-328x%2889%2990065-x
The distribution of 3 {GABAA} receptor α-subunit mRNAs in various regions of bovine brain has been investigated using in situ hybridization. Whereas the α2- and α3-transcripts...
Differential distribution in bovine brain of distinct γ-aminobutyric acid A receptor α-subunit mRNAs
Journal Article
WISDEN, W., MORRIS, B. J., DARLISON, M. G., HUNT, S. P., & BARNARD, E. A. (1989)
Differential distribution in bovine brain of distinct γ-aminobutyric acid A receptor α-subunit mRNAs. Transactions, 17(3), 566-567. https://doi.org/10.1042/bst0170566
No abstract available.
Influence of containing walls on the distribution of voidage in packed beds of uniform spheres
Journal Article
Kubie, J. (1988)
Influence of containing walls on the distribution of voidage in packed beds of uniform spheres. Chemical Engineering Science, 43(6), 1403-1405. https://doi.org/10.1016/0009-2509%2888%2985113-3
The distribution of voidage in the wall regions of randomly packed beds of uniform spheres is investigated. A general equation relating the local voidage to the distribution o...
Distinct GABAA receptor α subunit mRNAs show differential patterns of expression in bovine brain
Journal Article
Wisden, W., Morris, B. J., Darlison, M. G., Hunt, S. P., & Barnard, E. A. (1988)
Distinct GABAA receptor α subunit mRNAs show differential patterns of expression in bovine brain. Neuron, 1(10), 937-947. https://doi.org/10.1016/0896-6273%2888%2990151-1
Specific oligonucleotide probes have been used to visualize the regional and cellular distribution of the mRNAs encoding three structurally distinct GABA A receptor α subunits...
The Use of Sigmoids in Modelling and Forecasting Human Populations
Journal Article
Raeside, R. (1988)
The Use of Sigmoids in Modelling and Forecasting Human Populations. Journal of the Royal Statistical Â鶹ÉçÇø: Series A, 151(3), 499. https://doi.org/10.2307/2982997
The use of sigmoid trend models, particularly the logistic model, was once popular among demographers. However, by 1940 the approach had fallen out of favour, being criticized...
Brain α-Neurotoxin-Binding Proteins and Nicotinic Acetylcholine Receptors
Book Chapter
Darlison, M. G., Hicks, A. A., Cockcroft, V. B., Squire, M. D., & Barnard, E. A. (1988)
Brain α-Neurotoxin-Binding Proteins and Nicotinic Acetylcholine Receptors. In Cellular and Molecular Basis of Synaptic Transmission, 475-492. Springer Verlag. https://doi.org/10.1007/978-3-642-73172-3_32
The study of the nicotinic acetylcholine receptor (AChR) of skeletal muscle and fish electric organ has been greatly facilitated by the application of the α-neurotoxins (posts...
Automating Systems Development
Book
D. Benyon, & S. Skidmore (Eds.), (1988)
Automating Systems Development. https://doi.org/10.1007/978-1-4613-1033-4
1 INTRODUCTION These proceedings are the result of a conference on Automating Systems Development held at Leicester Polytechnic, England on 14 to 16 April 1987. The conference...
Pharmacology, Cloning and Expression of Insect Nicotinic Acetylcholine Receptors
Book Chapter
Marshall, J., David, J. A., Darlison, M. G., Barnard, E. A., & Sattelle, D. B. (1988)
Pharmacology, Cloning and Expression of Insect Nicotinic Acetylcholine Receptors. In Nicotinic Acetylcholine Receptors in the Nervous System, 257-281. Springer Verlag. https://doi.org/10.1007/978-3-642-74167-8_20
There is considerable evidence that acetylcholine is an excitatory neurotransmitter at many synapses in the insect central nervous system (Sattelle 1986). Despite the acute te...
Clinical trial of incontinence garments: recognition of the possible influence of the Hawthorne effect
Journal Article
Hanley, J., Beveridge, M., Aitken, C., Hunter, J., Dick, T., & Prescott, R. (1988)
Clinical trial of incontinence garments: recognition of the possible influence of the Hawthorne effect. Clinical Rehabilitation, 2(4), 285-290. https://doi.org/10.1177/026921558800200403
The results of clinical trials must be interpreted with care, recognizing that they may be affected by factors other than the items being tested. Different garments were routi...